Isavuconazonium (sulfate) |
| Catalog No.GC43911 |
El isavuconazonio (sulfato) (BAL8557-002), el profármaco del triazol activo Isavuconazol, es un agente antifúngico activo por vía oral.
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Cas No.: 946075-13-4
Sample solution is provided at 25 µL, 10mM.
Isavuconazonium is a water-soluble prodrug form of the azole antifungal isavuconazole (ISA). Oral administration of isavuconazonium increases survival in rat models of azole-susceptible and -resistant A. fumigatus infection when administered at doses ranging from 0.25 to 512 mg/kg per day (ISA-equivalent = 0.12-245.8 mg/kg per day). Isavuconazonium reduces fungal burden and organism-mediated pulmonary injury and increases survival in a rabbit model of experimental invasive pulmonary aspergillosis when administered at ISA-equivalent doses ranging from 40 to 60 mg/kg.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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