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ISIS 104838 sodium

Catalog No.GC70941

ISIS 104838 sodium is an antisense oligonucleotide agent that reduces the production of tumor necrosis factor (TNF-alpha), a substance that contributes to joint pain and swelling in rheumatoid arthritis.

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ISIS 104838 sodium Chemical Structure

Tamaño Precio Disponibilidad Cantidad
1 mg
270,00 $
Disponible
5 mg
693,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
ISIS 104838 sodium is an antisense oligonucleotide agent that reduces the production of tumor necrosis factor (TNF-alpha), a substance that contributes to joint pain and swelling in rheumatoid arthritis.

References:
[1]. Sewell KL, Geary RS, Baker BF, et al. Phase I trial of ISIS 104838, a 2'-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-alpha.J Pharmacol Exp Ther. 2002;303(3):1334-1343.

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