JNJ-1013 |
Catalog No.GC69316 |
JNJ-1013 es un inhibidor selectivo efectivo de la degradación de IRAK1, con valores IC50 respectivos para IRAK1, IRAK4 y VHL FP de 72, 443 y 1071 nM. JNJ-1013 induce apoptosis celular y aumenta la expresión del PARP clivado. JNJ-1013 reduce la expresión de IRAK1, p-IKBα y pSTAT3 (Tyr705).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2597343-08-1
Sample solution is provided at 25 µL, 10mM.
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