JNJ DGAT2-A |
| Catalog No.GC50285 |
JNJ DGAT2-A es un inhibidor selectivo de la diacilglicerol aciltransferasa 2 (DGAT2) con un valor IC50 de 0,14 μM en membranas de células de insectos Sf9 que expresan DGAT2 humana.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1962931-71-0
Sample solution is provided at 25 µL, 10mM.
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DGAT2 inhibitor (IC50 = 140 nM). Exhibits >70-fold selectivity for DGAT2 over DGAT1 and MGAT2.
Qi et al (2012) The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 J.Lipid Res. 53 1106 PMID:22493088 |Irshad et al (2017) Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes. J.Lipid Res. 58 15 PMID:27836993
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