KAT8 Inhibitor 19 (Synonyms: Lysine Acetyltransferase 8 Inhibitor 19) |
| Catalog No.GC91622 |
KAT8 inhibitor 19 is an inhibitor of lysine acetyltransferase 8 (KAT8; IC50 = 12.1 µM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 28532-21-0
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
KAT8 inhibitor 19 is an inhibitor of lysine acetyltransferase 8 (KAT8; IC50 = 12.1 µM).[1] It is selective for KAT8 over KAT2A, KAT2B, KAT3B, KAT6A, and KAT7 at 200 µM. KAT8 (50 µM) reduces histone 4 lysine 16 acetylation (H4K16Ac) in HT-29 colorectal carcinoma cells. It reduces the viability of HCT116, H1299, A549, and U937 cancer cells (IC50s = 39.4, 52.1, 41, and 30.1 µM, respectively).
References:
[1].Fiorentino, F., Sementilli, S., Menna, M., et al.First-in-class selective inhibitors of the lysine acetyltransferase KAT8J. Med. Chem.66(10)6591-6616(2023).
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *