KL101 (Synonyms: N-(2-(2,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)-3,4-dimethylbenzamide) |
| Catalog No.GB40252 |
KL101 (396721-89-4) is an isoform-selective stabilizer of the circadian clock protein CRY1. It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. KL101 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 396721-89-4
Sample solution is provided at 25 µL, 10mM.
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KL101 (396721-89-4) is an isoform-selective stabilizer of the circadian clock protein CRY1. It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. KL101 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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