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L-Tyrosine 15N

Catalog No.GC66023

L-Tyrosine-15N es la L-Tyrosine marcada con 15N. La L-tirosina es un aminoÁcido no esencial que puede inhibir la actividad de la citrato sintasa en la corteza posterior.

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L-Tyrosine 15N Chemical Structure

Cas No.: 35424-81-8

Tamaño Precio Disponibilidad Cantidad
10mg
93,20 $
Disponible
25mg
178,20 $
Disponible
50mg
283,50 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description of L-Tyrosine 15N

L-Tyrosine-15N is the 15N-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Chemical Properties of L-Tyrosine 15N

Cas No. 35424-81-8 SDF
Formula C9H1115NO3 M.Wt 182.18
Solubility H2O : 11.36 mg/mL (62.36 mM; ultrasonic and warming and adjust pH to 10 with NaOH and heat to 60°C) Storage 4°C, protect from light, stored under nitrogen
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of L-Tyrosine 15N

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.4891 mL 27.4454 mL 54.8908 mL
5 mM 1.0978 mL 5.4891 mL 10.9782 mL
10 mM 0.5489 mL 2.7445 mL 5.4891 mL
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In vivo Formulation Calculator (Clear solution) of L-Tyrosine 15N

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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