Laquinimod-d5 |
Catalog No.GC70633 |
Laquinimod-d5 (ABR-215062-d5) es deuterio etiquetado Laquinimod.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1214267-09-0
Sample solution is provided at 25 µL, 10mM.
Laquinimod-d5 (ABR-215062-d5) is deuterium labeled Laquinimod. Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator that prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing-remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research.
References:
[1]. Varrin-Doyer M, et al. Laquinimod, an up-and-coming immunomodulatory agent for treatment of multiple sclerosis. Exp Neurol. 2014 Dec;262 Pt A:66-71.
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