Lenalidomide-C5-amido-Boc |
| Catalog No.GC63474 |
Lenalidomide-C5-amido-Boc es el ligando de Cereblon basado en lenalidomida que se utiliza en el reclutamiento de la proteÍna CRBN. La lenalidomida-C5-amido-Boc se puede conectar al ligando de la proteÍna mediante un enlazador para formar PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2138441-25-3
Sample solution is provided at 25 µL, 10mM.
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Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC[1].
[1]. Wang, Shaomeng, et al. Preparation of phthalimide-based compounds as monofunctional intermediates for ligand-dependent target protein degradation. World Intellectual Property Organization, WO2017176958 A1 2017-10-12.
[2]. Robbins, Daniel, et al. WBifunctional compounds for degrading BTK via ubiquitin proteasome pathway. World Intellectual Property Organization, WO2021091575 A1 2021-05-14.
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