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Levodropropizine (Synonyms: (-)-(S)-Dropropizine)

Catalog No.GC15214

La levodropropizina (DF-526) es un inhibidor del receptor de histamina, la levodropropizina es un fÁrmaco antitusivo periférico eficaz y muy bien tolerado.

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Levodropropizine Chemical Structure

Cas No.: 99291-25-5

Tamaño Precio Disponibilidad Cantidad
50mg
50,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description of Levodropropizine

Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.

Chemical Properties of Levodropropizine

Cas No. 99291-25-5 SDF
Sinónimos (-)-(S)-Dropropizine
Chemical Name (2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol
Canonical SMILES C1CN(CCN1CC(CO)O)C2=CC=CC=C2
Formula C13H20N2O2 M.Wt 236.31
Solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Levodropropizine

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1 mg 5 mg 10 mg
1 mM 4.2317 mL 21.1586 mL 42.3173 mL
5 mM 0.8463 mL 4.2317 mL 8.4635 mL
10 mM 0.4232 mL 2.1159 mL 4.2317 mL
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In vivo Formulation Calculator (Clear solution) of Levodropropizine

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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