Limaprost-d3 (Synonyms: 17α,20-dimethyl-Δ2-PGE1-d3, 17α,20-dimethyl-Δ2-Prostaglandin E1-d3) |
| Catalog No.GC40239 |
Limaprost-d3 is intended for use as an internal standard for the quantification of limaprost by GC- or LC-MS.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1263190-37-9
Sample solution is provided at 25 µL, 10mM.
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Limaprost-d3 is intended for use as an internal standard for the quantification of limaprost by GC- or LC-MS. Limaprost is an analog of prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is orally active in both rats and guinea pigs at doses of 100 µg/kg as an inhibitor of ADP and collagen-induced platelet aggregation. Limaprost is 10-1,000 times more potent than PGE1 as an inhibitor of platelet adhesiveness measured in vitro. Intra-coronary injection (100 ng/kg) or intravenous injection (3 µg/kg) in anesthetized dogs causes vasodilation and increased coronary blood flow by 60-80%. Significant hypotensive effects were seen at 100 and 300 µg/kg orally in rats.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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