Lipoamido-PEG3-OH |
| Catalog No.GC67162 |
Lipoamido-PEG3-OH es un conector PROTAC basado en PEG que se puede utilizar en la síntesis de PROTAC. Lipoamido-PEG3-OH (compuesto TA-TEG-G2CN) se puede utilizar en la formación de una plataforma de administración de fármacos basada en nanopartículas de oro dendronizadas (AuNP) altamente estable.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1342764-64-0
Sample solution is provided at 25 µL, 10mM.
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Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Saha Ray A,et al. Set of Highly Stable Amine- and Carboxylate-Terminated Dendronized Au Nanoparticles with Dense Coating and Nontoxic Mixed-Dendronized Form.Langmuir. 2019 Mar 5;35(9):3391-3403.
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