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LY2880070

Catalog No.GC26113

LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.

Products are for research use only. Not for human use. We do not sell to patients.

LY2880070 Chemical Structure

Cas No.: 1375637-35-6

Tamaño Precio Disponibilidad Cantidad
1mg
38,00 $
Disponible
5mg
89,00 $
Disponible
10mg
133,00 $
Disponible
25mg
230,00 $
Disponible
50mg
311,00 $
Disponible
100mg
426,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description of LY2880070

LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.

Chemical Properties of LY2880070

Cas No. 1375637-35-6 SDF
Formula C19H23N7O2 M.Wt 381.43
Solubility DMSO: 60 mg/ml (157.3 mM) (< 1 mg/mL refers to the product slightly soluble or insoluble) Storage Powder: -20°C for 3 years,In solvent: -80°C for 2 years
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of LY2880070

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.6217 mL 13.1086 mL 26.2171 mL
5 mM 0.5243 mL 2.6217 mL 5.2434 mL
10 mM 0.2622 mL 1.3109 mL 2.6217 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of LY2880070

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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