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m-PEG-Succinimidyl Succinate (MW 5000)

Catalog No.GC60253

El succinato de m-PEG-succinimidil (MW 5000) es un conector PROTAC basado en PEG que se puede utilizar en la sÍntesis de PROTAC.

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m-PEG-Succinimidyl Succinate (MW 5000) Chemical Structure

Tamaño Precio Disponibilidad Cantidad
100mg
264,00 $
Disponible
250mg
426,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

m-PEG-Succinimidyl Succinate (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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