M617 TFA |
| Catalog No.GC61607 |
M617 TFA es un agonista selectivo del receptor de galanina 1 (GAL1), con Kis de 0,23 y 5,71 nM para GAL1 y GAL2, respectivamente.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
M617 TFA is a selective galanin receptor 1 (GAL1) agonist, with Kis of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617 TFA, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats[1][2].
[1]. LundstrÖm, L., et al. A Galanin Receptor Subtype 1 Specific Agonist. Int J Pept Res Ther 11, 17-27 (2005). [2]. Fang P, et al. Central injection of GalR1 agonist M617 facilitates GLUT4 expression in cardiac muscle of type 2 diabetic rats. Exp Gerontol. 2015;65:85-89.
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