Methoxyamine hydrochloride (Synonyms: O-Methylhydroxylamine hydrochloride) |
| Catalog No.GC26417 |
Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 593-56-6
Sample solution is provided at 25 µL, 10mM.
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Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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