Midostaurin-D5 (Synonyms: PKC412-d5; CGP 41251-d5) |
Catalog No.GC61064 |
La midostaurina-D5 (PKC412-D5) es una midostaurina marcada con deuterio. La midostaurina es un inhibidor de la proteÍna quinasa de mÚltiples objetivos que inhibe PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ y VEGFR1/2 con IC50 que van desde 22-500 nm.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Midostaurin-D5 (PKC412-D5) is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM[1].
[1]. Fabbro D, et al. Inhibitors of protein kinases: CGP 41251, a protein kinase inhibitor with potential as an anticancer agent. Pharmacol Ther. 1999 May-Jun;82(2-3):293-301.
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