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Midostaurin-D5 (Synonyms: PKC412-d5; CGP 41251-d5)

Catalog No.GC61064

La midostaurina-D5 (PKC412-D5) es una midostaurina marcada con deuterio. La midostaurina es un inhibidor de la proteÍna quinasa de mÚltiples objetivos que inhibe PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ y VEGFR1/2 con IC50 que van desde 22-500 nm.

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Midostaurin-D5 Chemical Structure

Tamaño Precio Disponibilidad Cantidad
1mg
482,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Midostaurin-D5 (PKC412-D5) is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM[1].

[1]. Fabbro D, et al. Inhibitors of protein kinases: CGP 41251, a protein kinase inhibitor with potential as an anticancer agent. Pharmacol Ther. 1999 May-Jun;82(2-3):293-301.

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