N-Desmethyl-loperamide (Synonyms: R 20905) |
| Catalog No.GC18538 |
An Analytical Reference Standard
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 66164-07-6
Sample solution is provided at 25 µL, 10mM.
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Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. N-Desmethyl-loperamide (dLop) is a major metabolite of loperamide. Like loperamide, dLop is a substrate of the ATP-dependent efflux transporter, P-glycoprotein. As a result, both the parent compound and the metabolite display restricted passage through the blood-brain barrier. dLop in biological samples can be analyzed by a variety of methods.
Review for N-Desmethyl-loperamide
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)
Review for N-Desmethyl-loperamide
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