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Nedosiran sodium

Catalog No.GC70681

Nedosiran sodium es un conjugalnac-dsrna diseñado para inhibir la producción de la enzima lactato deshidrogenasa hepática (LDH).

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Nedosiran sodium Chemical Structure

Cas No.: 2247026-22-6

Tamaño Precio Disponibilidad Cantidad
1 mg
306,00 $
Disponible
5 mg
765,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Nedosiran sodium is a GalNAc-dsRNA conjugate designed to inhibit production of the hepatic lactate dehydrogenase (LDH) enzyme.

References:
[1]. Kevin Shee, et al. Nedosiran Dramatically Reduces Serum Oxalate in Dialysis-Dependent Primary Hyperoxaluria 1: A Compassionate Use Case Report. Urology.2021 Oct;156:e147-e149.
[2]. Gema Ariceta, et al. Hepatic Lactate Dehydrogenase A: An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria. Kidney Int Rep.2021 Feb 3;6(4):1088-1098.
[3]. Thomas A Forbes, et al. Therapeutic RNA interference: A novel approach to the treatment of primary hyperoxaluria. Br J Clin Pharmacol.2021 May 22.

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