Netilimicin (sulfate) |
Catalog No.GC44371 |
Netilimicin is an aminoglycoside antibiotic.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 56391-57-2
Sample solution is provided at 25 µL, 10mM.
Netilimicin is an aminoglycoside antibiotic. It is active against S. aureus, N. gonorrhoeae, E. coli, P. mirabilis, and P. aeruginosa (MICs = 0.4, 3.1, 0.8, 1.6, and 0.4 µg/ml, respectively) as well as Enterococci, Enterobacter, Citrobacter, and Klebsiella species (MICs = 3.1, 0.4, 0.8, and ≤0.2 µg/ml, respectively). Netilimicin induces nephrotoxicity in rats when administered at doses ranging from 50 to 150 mg/kg. It also induces neuromuscular block, decreasing twitch tension in isolated diaphragm and soleus muscles in rabbits (ED50s = 18.5 and 62.2 mg/kg, respectively). Formulations containing netilimicin were previously used in the intravenous treatment of severe bacterial infections.
Average Rating: 5
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