O-Desmethyl Midostaurin-d5 (Synonyms: CGP62221-d5; O-Desmethyl PKC412-d5) |
Catalog No.GC61148 |
O-Desmetil PKC412-d5 (CGP62221-d5) es un O-Desmetil PKC412 marcado con deuterio. La O-desmetil midostaurina (CGP62221; O-desmetil PKC412) es el metabolito activo de la midostaurina a través del metabolismo de las enzimas hepÁticas del citocromo P450.
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Sample solution is provided at 25 µL, 10mM.
O-Desmethyl PKC412-d5 (CGP62221-d5) is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin via cytochrome P450 liver enzyme metabolism[1].
[1]. Levis M, et al. Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors. Blood. 2006 Nov 15;108(10):3477-83.
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