PARP14 inhibitor H10 |
Catalog No.GC39302 |
El inhibidor H10 de PARP14, compuesto H 10, es un inhibidor selectivo contra PARP14 (IC50=490 nM), sobre otras PARP (≈24 veces sobre PARP1). El inhibidor H10 de PARP14 induce la apoptosis celular mediada por caspasa-3/7.
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Cas No.: 2084811-68-5
Sample solution is provided at 25 µL, 10mM.
PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis[1].
[1]. Peng B, et al. Small Molecule Microarray Based Discovery of PARP14 Inhibitors. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253.
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