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PARP14 inhibitor H10

Catalog No.GC39302

El inhibidor H10 de PARP14, compuesto H 10, es un inhibidor selectivo contra PARP14 (IC50=490 nM), sobre otras PARP (≈24 veces sobre PARP1). El inhibidor H10 de PARP14 induce la apoptosis celular mediada por caspasa-3/7.

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PARP14 inhibitor H10 Chemical Structure

Cas No.: 2084811-68-5

Tamaño Precio Disponibilidad Cantidad
1mg
274,00 $
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5mg
881,00 $
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10mg
1.474,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis[1].

[1]. Peng B, et al. Small Molecule Microarray Based Discovery of PARP14 Inhibitors. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253.

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