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PEG4-sulfonic acid

Catalog No.GC67080

El ácido PEG4-sulfónico es un conector PROTAC basado en PEG que se puede utilizar en la síntesis de PROTAC.

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PEG4-sulfonic acid Chemical Structure

Cas No.: 173459-90-0

Tamaño Precio Disponibilidad
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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