PF 04418948 |
| Catalog No.GC11067 |
PF 04418948 es un antagonista del receptor de prostaglandina EP2 activo por vía oral, potente y selectivo con una IC50 de 16 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1078166-57-0
Sample solution is provided at 25 µL, 10mM.
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PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM.
References:
[1]. af Forselles KJ, et al. In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP2 receptor antagonist. Br J Pharmacol. 2011 Dec;164(7):1847-1856.
[2]. Birrell MA, et al. Selectivity profiling of the novel EP2 receptor antagonist, PF-04418948, in functional bioassay systems: atypical affinity at the guinea pig EP2 receptor. Br J Pharmacol. 2013 Jan;168(1):129-138.
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