Phox-I2 |
| Catalog No.GC70477 |
Phox-I2 es un inhibidor selectivo de la interacción p67phox-Rac1, se une a p67phox con alta afinidad con un Kd de ~150 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 353495-22-4
Sample solution is provided at 25 µL, 10mM.
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Phox-I2 is effective in inhibiting NOX2-mediated superoxide production dose-dependently in dHL-60 cells and primary human neutrophils without detectable toxicity[1].
References:
[1]. Emily E Bosco, et al. Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation. Chem Biol. 2012 Feb 24;19(2):228-42.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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