Pinosylvin (Synonyms: trans-3,5-Dihydroxystilbene) |
| Catalog No.GC40861 |
La pinosilvina es una toxina estilbenoide preinfecciosa aislada del duramen de Pinus spp, tiene actividades antibacterianas.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 22139-77-1
Sample solution is provided at 25 µL, 10mM.
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Pinosylvin is a stilbene originally isolated from pine heartwood that has diverse biological activities. It activates sirtuin 1 (SIRT1) and induces glucose uptake in isolated rat L6 skeletal muscle myotubes. Pinosylvin reduces radial growth in a panel of 28 plant pathogenic fungi when used at a concentration of 100 μg/ml. It reduces expression of matrix metalloproteinase-2 (MMP-2), MMP-9, and membrane type 1-MMP in and inhibits migration of HT-1080 cells. Pinosylvin (10 mg/kg, i.p.) reduces the number of tumor nodules and lung tumor weight in a CT26 mouse xenograft model of metastatic colon cancer. It decreases hind paw volume and myeloperoxidase (MPO) activity in a rat model of adjuvant-induced arthritis. Pinosylvin also exhibits plant antifeedant activity against L. americanus (snowshoe hares).
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