Platyconic acid A |
| Catalog No.GC63649 |
El Ácido platicÓnico A es un componente activo de las saponinas changkil de platycodon grandiflorum y se puede utilizar para la investigaciÓn de la reducciÓn de la inflamaciÓn de las vÍas respiratorias.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 68051-23-0
Sample solution is provided at 25 µL, 10mM.
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Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation[1].
Platyconic Acid A (0.5~2 μM; 30 minutes; A549 cells) inhibits PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner[1].Platyconic Acid A (0.5~2 μM; 24 hours; A549 cells) decreases PMA-increased MUC5AC mRNA expression in a concentration-dependent manner[1].
[1]. Choi JH, et al. Saponins, especially platyconic acid A, from Platycodon grandiflorum reduce airway inflammation in ovalbumin-induced mice and PMA-exposed A549 cells. J Agric Food Chem. 2015;63(5):1468-1476.
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