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PM-43I

Catalog No.GC71016

PM-43I es un potente inhibidor de STAT6 y puede reducir el nivel de fosforilación de STAT6.

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PM-43I Chemical Structure

Cas No.: 1637532-77-4

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL DMSO)
1.272,00 $
Disponible
1 mg
248,00 $
Disponible
5 mg
743,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
PM-43I is a potent STAT6 inhibitor and can reduce STAT6 phosphorylation level. PM-43I can be used in allergic lung disease, allergic rhinitis, chronic pulmonary obstructive disease and cancer research[1].

PM-43I (0.05-5 μM; 2 h) inhibits IL-4 stimulated phosphorylation of STAT6 in Beas-2B immortalized human airway cells[1].

PM-43I (intranasal administration; 5 μg per mouse; every other day; 18 d) activity is restricted to the lung by intranasal administration[1].

References:
[1]. John S. Mcmurray, et al. Stat6 inhibitors. WO2014182928A2.

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