Pomalidomide 4'-PEG5-amine (hydrochloride) |
| Catalog No.GC91582 |
Pomalidomide 4’-PEG5-amine is a PEGylated form of the cereblon (CRBN) inhibitor pomalidomide .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2357117-23-6
Sample solution is provided at 25 µL, 10mM.
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Pomalidomide 4’-PEG5-amine is a PEGylated form of the cereblon (CRBN) inhibitor pomalidomide .[1],[2] It has been conjugated to various ligands in the development of proteolysis-targeting chimeras (PROTACs).
References:
[1].Cheng-Sánchez, I., Gosselé, K.A., Palaferri, L., et al.Discovery and characterization of active CBP/EP300 degraders targeting the HAT domainACS Med. Chem. Lett.15(3)355-361(2024).
[2].Zhu, S., Liu, J., Xiao, D., et al.Design, synthesis, and biological evaluation of Wee1 kinase degradersEur. J. Med. Chem.243:114786(2022).
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