- Cat.No. Nombre del producto Información
- GC45379 Alloxan (hydrate) A toxin that selectively eliminates pancreatic β-cells
- GC30007 4-Azido-L-phenylalanine (p-Azidophenylalanine) La 4-azido-L-fenilalanina (p-azidofenilalanina) es un aminoÁcido no natural que se utiliza como indicador vibratorio eficaz de los entornos proteicos locales.
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GC11940
5-BrdU
BrdU, Bromodeoxyuridine, Broxuridine, NSC 38297
Synthetic thymidine analog - GA20580 Ac-Ile-Glu-Pro-Asp-pNA Ac-Ile-Glu-Pro-Asp-pNA (Ac-IEPD-pNA) is a colorimetric substrate for granzyme B (GzmB) and caspase-8. Granzyme B and caspase-8 preferentially bind and cleave the Ile-Glu-Pro-Asp (IEPD) peptide sequence, and the catalytic activity of the enzyme is indirectly measured by detecting the release of p-nitroaniline (pNA), which is measured by the optical density (OD) at 405 nm.
- GC12259 Azidobutyric acid NHS ester Azidobutyric acid NHS ester is a heterobifunctional crosslinker mainly used for the azido labeling of amino-containing biomolecules.
- GC32732 Hyaluronic acid Hyaluronic acid (HA) is a biopolymer composed of repeating units of disaccharides, which include molecules of D-glucuronic acid and N-acetylglucosamine molecules linked by β- (1 4) and β- (1 3)glycosides.
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GC11551
Hydrocortisone
Cortisol, Dihydrocostisone, NSC 10483
Hydrocortisone, a natural glucocorticoid secreted by adrenal and extra-adrenal tissues -
GC40717
Hyocholic Acid
γ-Muricholic Acid
El ácido hiólico es un ácido biliar primario en cerdos y otros mamíferos.
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GC60235
Maleimide-DOTA
Maleimido-mono-amide-DOTA
Maleimide-DOTA is a non-degradable ADC linker used in antibody drug conjugate (ADC) synthesis[1]. -
GC61092
MSA-2
5,6-dimethoxy-γ-oxo-benzobthiophene-2-Butanoic Acid
A STING agonist -
GC46194
OSW-1
Orsaponin
A saponin with antiviral and anticancer activities - GA23531 Suc-Ala-Ala-Pro-Ile-pNA Suc-Ala-Ala-Pro-Ile-pNA (Suc-AAPI-pNA) is a synthetic peptide compound used as a substrate for detecting and studying the activity of various proteases. Under the action of enzymes, Suc-Ala-Ala-Pro-Ile-pNA is hydrolyzed, releasing yellow p-nitroaniline (pNA). The change in absorbance at 400-410 nm is measured by colorimetry to reflect enzyme activity.
- GC10254 AdipoRon AdipoR1 and AdipoR2 agonist, first orally active
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GC17256
Pilocarpine HCl
NSC 5746
Pilocarpine HCl is a miotic drug that acts as a M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist - GC15064 Purmorphamine Purmorphamine is the first small molecule agonist developed for Smoothened protein.
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GC36041
Fibronectin Adhesion-promoting Peptide
Heparin Binding Peptide
Fibronectin Adhesion-promoting Peptide is a potent inducer of stress fibers and focal adhesion in fibroblasts. -
GC44258
Myristic Acid Alkyne
13-alkyne Myristic Acid
Myristic Acid Alkyne es un conector PROTAC basado en una cadena de alquilo que se puede utilizar en la sÍntesis de PROTAC. - GA23894 Z-Phe-Arg-AMC . HCl Z-Phe-Arg-AMC is a substrate for serine proteases, including cathepsins, kallikrein and plasmin.
- GC17681 Gap19 Gap19 (KQIEIKKFK) blocks HCs but not GJCs and is specific for Cx43.
- GC13886 ω-Conotoxin GVIA ω-Conotoxin GVIA is a cone snail toxin that selectively blocks N-type channels in neurons .
- GC17784 JMV 449 JMV 449 is a potent, long-lasting neurotensin receptor agonist
- GC30416 Mitoquinone (MitoQ) Mitoquinone (MitoQ) is a ubiquinone-derived antioxidant
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GC14843
Serotonin HCl
5-HT, 5-Hydroxytryptamine
Endogenous 5-HT receptor agonist - GC33975 Ampicillin (D-(-)-α-Aminobenzylpenicillin) La ampicilina es un antibiÓtico betalactÁmico de amplio espectro contra una variedad de bacterias grampositivas y gramnegativas.
- GD21958 1,1,2,2-Tetrafluoroethyl methyl ether
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GC40719
β-Muricholic Acid
5β-Cholanic Acid-3α,6β,7β-triol, β-MCA
A murine-specific primary bile acid - GC41233 (R)-MG132 A potent proteasome inhibitor
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GC42033
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
1-Palmitoyl-2-Oleoyl-sn-glycero-3-Phosphocholine, 1,2POPC
A synthetic phosphatidylcholine -
GC12757
17-ODYA
Alk-16
LTB4 ω-hydroxylase inhibitor -
GC42410
4-hydroxy Nonenal
4-HNE
A lipid peroxidation product - GC35250 Adenosine deaminase Involved in metabolism of purines
- GC15717 AM251 A potent CB1 antagonist
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GC39339
Anakinra
AMG-719
Anakinra (Raleukin) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. -
GC18109
Astragaloside A
AS-A, AST-A, Astramembrannin I
anti-hypertension, positive inotropic action, anti-inflammation, and anti-myocardial injury -
GC62253
Camrelizumab
SHR-1210
Camrelizumab (SHR-1210) es un potente anticuerpo monoclonal (mAb) IgG4-κ humanizado de alta afinidad contra PD-1. Camrelizumabse une a PD-1 con una alta afinidad de 3 nM e inhibe la interacciÓn de uniÓn de PD-1 y PD-L1 con una IC50 de 0,70 nM. Camrelizumab actÚa como un agente anti-PD-1/PD-L1 y se puede utilizar para la investigaciÓn del cÁncer, incluidos NSCLC, ESCC, linfoma de Hodgkin y HCC avanzado et al. -
GC16661
Citrinin
NSC 186
A mycotoxin inducing apoptosis -
GC15319
Cyclosporin H
5-(N-methyl-D-valine)-Cyclosporin A, Sandoz 37-839
Selective and competitive formyl peptide receptor antagonist -
GC16315
D-AP5
D-2-Amino-5-Phosphonovaleric acid; D-APV
A NMDA antagonist -
GC38906
DS18561882
DS18561882 es un inhibidor altamente potente y selectivo de la isoenzima metilentetrahidrofolato deshidrogenasa 2 (MTHFD2) con un valor de IC50 de 0,0063 μM. DS18561882 también tiene efecto inhibitorio sobre MTHFD1 (IC50=0,57 μM). DS18561882 presenta un buen perfil farmacocinético oral.
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GC13391
Exendin-4
Exendin-4, un agonista del receptor de la proteína 1 similar al glucagón (GLP-1), imita la actividad de la hormona incretina mamífera péptido similar al glucagón 1 (GLP-1) y, por lo tanto, promueve la secreción de insulina y funciona en el control de la glucosa.
- GC36383 KAN0438757 KAN0438757 es un inhibidor potente y selectivo de la quinasa metabÓlica PFKFB3 con una IC50 de 0,19 μM.
- GC12467 KPT-330 CRM1 inhibitor, orally bioavailable and selective
- GC18338 Laurdan A fluorescent membrane probe
- GC14045 Loreclezole GABAA receptor modulator
- GC14793 MK 0893 MK 0893 is a potent and selective glucagon receptor (GCGR) antagonist with an IC50 value of 6.6 nM.
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GC38819
ML334
LH601
An inhibitor of the Nrf2-Keap1 protein-protein interaction -
GC13386
ML351
CID 664510
human reticulocyte 15-LOX-1 inhibitor -
GC19225
PD-1-IN-1 (CA-170)
CA-170
PD-1-IN-1 (CA-170) es un inhibidor dual administrado por vÍa oral de VISTA y PD-L1. - GC11869 SZL P1-41 Skp2 inhibitor
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GC37845
Tucidinostat
CS 055, HBI 8000, Tucidinostat
An HDAC inhibitor - GC16738 Tunicamycin Mixture Antibiotic,inhibits GlcNAc phosphotransferase (GPT)
- GC19976 TVB-3664 TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively.
- GC11245 XMU-MP-1 MST1/2 inhibitor, potent and selective
- GC12287 Z-DEVD-FMK Z-DEVD-FMK is a specific irreversible cysteine-aspartic protease 3 (caspase-3) inhibitor with an IC50 of 18μM.
- GA20196 (Gly¹⁴)-Humanin (human) Humanin is both an intracellular protein and a secreted protein.
- GA20228 (Leu¹⁵)-Gastrin I (human) Gastrin is gastrointestinal hormones
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GC12405
ABT-263 (Navitoclax)
Navitoclax,ABT-263,ABT263,ABT 263
ABT-263 (Navitoclax) es un inhibidor de Bcl-xL, Bcl-2 y Bcl-w, con Ki ≤0.5 nM, ≤1 nM y ≤1 nM respectivamente. - GC19061 BAY-876 BAY-876 es un inhibidor selectivo del transportador de glucosa 1 (GLUT1) con un IC50 de 2 nM. El IC50 de BAY-876 para GLUT2, GLUT3 y GLUT4 son 10.8, 1.67 y 0.29μM, respectivamente.
- GC11032 Cl-Amidine (trifluoroacetate salt) PAD4 deimination activity inhibitor
- GC10395 Dynasore Dynasore, as a GTPase inhibitor, can rapidly and reversibly inhibit dynamin activity, which prevents endocytosis.
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GC34011
FX-11 (LDHA Inhibitor FX11)
LDHA Inhibitor FX11
FX-11 (LDHA Inhibitor FX11) was found to be a potent, competitive inhibitor of the human LDH-A's NADH binding pocket. -
GC10359
GANT61
NSC 136476
GANT61 was able to efficiently block GLI1 as well as GLI2-induced transcription, IC50 is 5 µM. -
GC14102
Genistein
CI-75610, NSC 36586
Genistein is an isoflavone belonging to the flavonoid group of compounds and is found in a number of plants. -
GC19553
Gentamicin
Gentamicin; Centicin; Lyramycin; Oksitselanim; Refobacin; Septigen; Uromycine;
Gentamicin is an aminoglycoside bactericidal antibiotic that is effective against Gram-negative bacterial infections. -
GC19482
Gilteritinib
ASP2215
Gilteritinib (ASP2215, Xospata) for relapsed and /or refractory AML (R/R AML). -
GC18201
Gly-Pro-pNA (hydrochloride)
Gly-Pro pnitroanilide, GP-pNA
Gly-Pro-pNA (hydrochloride) is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). -
GC16907
Go 6983
Goe 6983;Go6983;Go-6983
Go 6983 (GÖ 6983) is one of the bisindolylmaleimide group of PKC inhibitor compounds, Go 6983 (GÖ 6983) was able to differentiate between PKC mu and other PKC isoenzymes. -
GC43783
Green CMFDA
5-Chloromethylfluorescein diacetate
Green CMFDA, as a non-terminal, non-fluorescent probe, can be cleaved by non-specific esterases common to living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope. - GC19175 GSK-872 GSK-872 is a RIPK3 inhibitor.
- GC13696 GSK690693 GSK690693 is an ATP-competitive, low nanomolar inhibitor of Akt kinases with IC50 values of 2, 13, and 9 nM for Akt1, 2, and 3, respectively.
- GC38465 GsMTx4 GsMTx4 selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families.
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GC36196
Guadecitabine sodium
SGI-110 sodium; S-110 sodium
Guadecitabine is a novel hypomethylating dinucleotide of decitabine and deoxyguanosine that is resistant to degradation by cytidine deaminase. - GC10975 GW4064 GW4064, as a synthetic FXR agonist, was used for treatment of cholestatic liver diseases, metabolic syndrome and alcoholic liver disease.
- GC19186 GW4869 GW4869 is a noncompetitive neutral sphingomyelinase(N-SMase) inhibitor with an IC50 of 1 uM.
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GC10074
H 89 2HCl
5Isoquinolinesulfonamide, Protein Kinase Inhibitor H89
H-89 2HCl is A potent and selective camp-dependent protein kinase A inhibitor with IC50 value of 48 nM, showing weak inhibition of PKG,PKC,Casein kinase and other kinases. - GA22973 H-Tyr-His-OH H-Tyr-His-OH was maintained as an internal standard for histidine quantitative analysis and eluted at 8.06 min.
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GC30006
H2DCFDA (DCFH-DA)
DCFH, DCFHDA
H2DCFDA(DCFH-DA) is a redox-sensitive fluorescent probe, which could be used to measure intracellular reactive oxygen species levels - GC60186 HBC620 HBC620 is an analog of HBC, which is a GFP fluorophore-like synthetic dye with a structurally rigid electron acceptor and a strong electron donor.
- GC14591 Hemin chloride Hemin chloride, a substrate of heme oxygenase (HO)-1, induces HO-1 expression on a variety of cells to exert anti-oxidant and anti-inflammatory roles.
- GC10398 Heparin sodium Heparin sodium, as as anti-coagulants, belongs to a class of glucans, which can interact with a variety of proteins to produce a variety of biological activities.
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GC40103
Herboxidiene
GEX1A, Tan 1609
Herboxidiene, as a potent antitumor agent, can target the SF3B subunit of the spliceosome. Herboxidiene also induces both G1 and G2/M cell cycle arrest in a human normal fibroblast cell line WI-38. -
GC11719
HG-9-91-01
HG-9-91-01 is a salt-inducible kinases (SIK) inhibitor, inhibited SIK1, SIK2, SIK3 with IC50 values of 0.92nM, 6.5nM and 19.4nM, respectively.
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GC15308
IAA-94
R(+)-IAA 94
IAA-94 (Indanyloxyacetic acid-94) is an intracellular chloride channel blocker. - GC19194 IACS-10759 IACS-10759 (IACS-010759) is an oxidative phosphorylation inhibitor, IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation ( OXPHOS ).
- GC38096 Icaritin Icaritin is a prenylflavonoid derivative obtained from the Epimedium genus.
- GP11075 Imipenem Imipenem es una tienamicina semisintética.
- GC19533 Infliximab Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α.
- GC31303 Insulin(cattle) (Insulin from bovine pancreas) Insulin is a hormonal protein consisting of two chains of 21 and 30 amino acids.
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GC13681
INT-777
6-EMCA, S-EMCA, HY-15677
INT-777 is a novel specific semisynthetic TGR5 agonist used for alleviating cardiomyocyte injury and improving cognitive impairment and synaptic dysfunction in mice model of AD. - GC15446 Ionomycin free acid Ionomycin free acid is a selective and potent calcium ion carrier that acts as an active Ca2+ carrier.
- GC30558 IRBP (1-20), human IRBP (1-20), human is the 1-20 amino acid fragment of the optical interreceptor retinoid binding protein (IRBP).
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GC17108
ISO-1
ISO1, Macrophage Migration Inhibitory Factor
ISO-1 inhibited MIF tautomerase activity in a dose-dependent manner with an IC50 of about 7 µM. - GC19209 JNJ-63533054 JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16nM
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GC11438
JSH-23
NFκB Activation Inhibitor II
JSH-23, exhibited inhibitory effect on nuclear translocation and NF-κB transcriptional activity with an IC50 value of 7.1 µM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7.
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GC17385
KML 29
KML 29 is reported to display IC50 values of 43, 15, and 5.9 nM toward rat, mouse, and human monoacylglycerol lipase (MAGL), respectively.
- GC32452 KP-457 KP-457 es un inhibidor selectivo de ADAM17, que tiene una estructura de reverse-hidroxamato.
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GC41478
L-α-Hydroxyglutaric Acid
2(S)-HG, 2(S)-Hydroxyglutaric Acid, L-2-HG, L-2-Hydroxyglutaric Acid
L-α-Hydroxyglutaric Acid is an important metabolite in various domains of life. In mammals and plants, it is produced by lactate dehydrogenase (LDH) and malate dehydrogenase (MDH)-mediated 2-ketoglutarate (2-KG) reduction under hypoxic conditions. -
GA11233
L-NAME hydrochloride
LNGNitroarginine methyl ester, N(G)-NitroL-arginine methyl ester
L-NAME hydrochloride se ha utilizado ampliamente para inhibir la sintasa de óxido nítrico (NOS) constitutiva en diferentes sistemas biológicos. - GC33822 Larazotide acetate Larazotide acetate (formerly AT-001) is a highly polar octapeptide, derived from a prokaryotic zonula occludens protein secreted by Vibrio cholera.
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GC19220
Lemborexant
E-2006
Lemborexant (E2006) is an oral active diorexin receptor antagonist (DORA) and has been approved by the US Food and Drug Administration for the treatment of insomnia.