RAGE antagonist peptide |
Catalog No.GC50401 |
El péptido antagonista de RAGE es un antagonista de productos finales de glicaciÓn avanzada (RAGE).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1092460-91-7
Sample solution is provided at 25 µL, 10mM.
Receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and RAGE-mediated NF-κB activity in human PDAC cell lines. Inhibits effects of TDI exposure in BALB/c mice.
Arumugam et al (2012) S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis. Clin.Cancer.Res. 18 4356 PMID:22718861 |Yao et al (2016) The receptor for advanced glycation end products is required for beta -catenin stabilization in a chemical-induced asthma model. Br.J.Pharmacol. 173 2600 PMID:27332707
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