δ12-Prostaglandin J2 (Synonyms: Δ12PGJ2) |
Catalog No.GC41109 |
δ12-Prostaglandin J2 (δ12-PGJ2) es una prostaglandina de ciclopentenona (PG) con efecto antiproliferativo en el crecimiento de varias células tumorales. δ12-prostaglandina J2, un producto de deshidrataciÓn natural de la prostaglandina D2, es capaz de inducir la apoptosis en las células HeLa a través de la activaciÓn de la caspasa.
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Cas No.: 87893-54-7
Sample solution is provided at 25 µL, 10mM.
δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 µg/ml. δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng. It is also a moderately potent PPARγ ligand.
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