AZD-5069 |
| Catalog No.GC32707 |
AZD-5069 es un potente antagonista del receptor de quimiocinas CXCR2, utilizado para el tratamiento del cÁncer.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 878385-84-3
Sample solution is provided at 25 µL, 10mM.
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AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.
AZD-5069 (Compound 2) acts as CXCR2 antagonist by inhibition of [125I]-IL-8 binding to human CXCR2 receptors and as inhibitor of GROα-induced Ca2+ flux in human neutrophils loaded with fluo-3 dye[1].
[1]. Norman P. Evidence on the identity of the CXCR2 antagonist AZD-5069. Expert Opin Ther Pat. 2013 Jan;23(1):113-7.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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