BAY 707 |
| Catalog No.GC50656 |
BAY 707 es un inhibidor de MTH1 (NUDT1) altamente potente y selectivo competitivo con el sustrato con una IC50 de 2,3 nM. BAY 707 tiene un buen perfil farmacocinético (FC) frente a otros compuestos MTH1 y es bien tolerado en ratones, pero muestra una clara falta de eficacia anticancerígena in vitro o in vivo.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2109805-96-9
Sample solution is provided at 25 µL, 10mM.
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Potent and selective MTH1 inhibitor (IC50 = 2.3 nM). Exhibits no significant activity at 1 μM concentration against a panel of 97 kinases. Cell-permeable and active in vivo. Displays no antitumor activity in vitro or in vivo.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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