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BRACO 19 trihydrochloride

Catalog No.GC50140

El triclorhidrato de BRACO 19 es un potente inhibidor de la telomerasa/telómero, que previene la acción catalítica y de protección de la telomerasa.

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BRACO 19 trihydrochloride Chemical Structure

Cas No.: 1177798-88-7

Tamaño Precio Disponibilidad Cantidad
10 mg
316,00 $
Disponible
50 mg
1.327,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

Telomerase inhibitor (IC50 = 115 nM). Inhibits expression of human telomerase reverse transcriptase (hTERT), induces cellular senescence and inhibits growth of uterine cancer cells in vitro. Inhibits growth of uterine tumor xenografts in mice.

Gowan et al (2002) A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity. Mol.Pharmacol. 61 1154 PMID:11961134 |Burger et al (2005) The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function. Cancer Res. 15 1489 PMID:15735037

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Review for BRACO 19 trihydrochloride

Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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