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Inicio >> Signaling Pathways >> Cardiovascular >> Atherosclerosis

Atherosclerosis

Products for  Atherosclerosis

  1. Cat.No. Nombre del producto Información
  2. GC48283 α-Linolenic Acid-d14

    ALAd14

     An internal standard for the quantification of αLinolenic acid α-Linolenic Acid-d14 Chemical Structure
  3. GC40467 (±)11-HETE

    (±)11-Hydroxyeicosatetraenoic Acid

     (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. (±)11-HETE Chemical Structure
  4. GC41649 (±)13-HODE cholesteryl ester (±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. (±)13-HODE cholesteryl ester Chemical Structure
  5. GC41666 (±)9-HODE cholesteryl ester (±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. (±)9-HODE cholesteryl ester Chemical Structure
  6. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt) Chemical Structure
  7. GC46496 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC

    18:0/20:4-d8-PC, PC(18:0/20:4-d8), SAPCd8, 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-Phosphatidylcholine, 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-Phosphocholine

     An internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC 1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC Chemical Structure
  8. GC41893 13(R)-HODE cholesteryl ester 13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 13(R)-HODE cholesteryl ester Chemical Structure
  9. GC41895 13(S)-HODE cholesteryl ester 13(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 13(S)-HODE cholesteryl ester Chemical Structure
  10. GC41897 13(S)-HOTrE 13(S)-HOTrE is the 15-lipoxygenase (15-LO) product of linolenic acid. 13(S)-HOTrE Chemical Structure
  11. GC49671 2,3-Oxidosqualene

    (3R,S)-Oxidosqualene, Squalene 2,3-oxide

     An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  12. GC41614 24-dehydro Cholesterol

    Desmosterol

    El 24-deshidrocolesterol es una molécula similar al colesterol.

     24-dehydro Cholesterol Chemical Structure
  13. GC46243 24-dehydro Cholesterol-d6

    Desmosterol-d6

     An internal standard for the quantification of 24-dehydro cholesterol 24-dehydro Cholesterol-d6 Chemical Structure
  14. GC46528 25-hydroxy Cholesterol-d6 An internal standard for the quantification of 25hydroxy cholesterol 25-hydroxy Cholesterol-d6 Chemical Structure
  15. GC42411 4-hydroxy Nonenal Alkyne

    Click Tag 4HNE Alkyne

    4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.

     4-hydroxy Nonenal Alkyne Chemical Structure
  16. GC40053 5α,6α-epoxy Cholestanol

    NSC 18176

     An oxysterol and a metabolite of cholesterol produced by oxidation 5α,6α-epoxy Cholestanol Chemical Structure
  17. GC45357 5-Chlorouracil   5-Chlorouracil Chemical Structure
  18. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone Chemical Structure
  19. GC40202 7α-hydroxy Cholesterol-d7

    7α-hydroxycholesterol-d7

    7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

     7α-hydroxy Cholesterol-d7 Chemical Structure
  20. GC46241 7-keto Cholesterol-d7

    7-oxo Cholesterol-d7

    7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL

     7-keto Cholesterol-d7 Chemical Structure
  21. GC42634 9(R)-HODE cholesteryl ester 9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 9(R)-HODE cholesteryl ester Chemical Structure
  22. GC19460 9(S)-HODE 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. 9(S)-HODE Chemical Structure
  23. GC42635 9(S)-HODE cholesteryl ester 9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. 9(S)-HODE cholesteryl ester Chemical Structure
  24. GC49784 AZD 2716 An sPLA2 inhibitor AZD 2716 Chemical Structure
  25. GC42890 Azelaoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ. Azelaoyl PAF Chemical Structure
  26. GC46912 Beauveriolide III Beauveriolide III es un inhibidor de la formaciÓn de gotas de lÍpidos en macrÓfagos de ratÓn. Beauveriolide III Chemical Structure
  27. GC42924 Beraprost (sodium salt)

    ML 1129, Procyclin, TRK 100

     Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. Beraprost (sodium salt) Chemical Structure
  28. GC42994 Butanoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate polymorphonuclear leukocytes. Butanoyl PAF Chemical Structure
  29. GC43136 Campestanol

    24-Methyl-5α-cholestan-3β-ol

     El campestanol es un fitosterol que se puede encontrar en los alimentos vegetales. Campestanol Chemical Structure
  30. GC43160 CAY10485

    3,4dihydroxy Hydrocinnamic acid (LAspartic acid dibenzyl ester) amide

     Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10485 Chemical Structure
  31. GC41636 CAY10487

    3,4Dihydrocinnamic Acid (Lalanine methyl ester) amide

     The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 Chemical Structure
  32. GC40203 Cholesterol-d6

    Provitamin D-d6

    Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS.

     Cholesterol-d6 Chemical Structure
  33. GC47085 Cholesterol-d7

    Provitamin D-d7

     An internal standard for the quantification of cholesterol Cholesterol-d7 Chemical Structure
  34. GC19433 Cholesteryl Heptadecanoate

    Cholesteryl Margarate, Heptadecanoic Acid cholesteryl ester, Margaric Acid cholesteryl ester

     Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations. Cholesteryl Heptadecanoate Chemical Structure
  35. GC43263 Cholesteryl Stearate

    18:0 CE, 18:0 Cholesterol ester, CE(18:0), Cholesterol Stearate, NSC 59693

     Cholesteryl stearate is a cholesterol ester. Cholesteryl Stearate Chemical Structure
  36. GC45439 Docosahexaenoic Acid-d5 MaxSpec• Standard

    Cervonic Acid-d5, C22:6(4Z,7Z,10Z,13Z,16Z,19Z)-d5, C22:6 n-3-d5, DHA-d5, 4,7,10,13,16,19-Docosahexaenoic acid-d5

     Ácido docosahexaenoico-d5 MaxSpec• EstÁndar (DHA-d5) es el Ácido docosahexaenoico marcado con deuterio. Docosahexaenoic Acid-d5 MaxSpec• Standard Chemical Structure
  37. GC52193 Eptifibatide La eptifibatida es un heptapéptido cÍclico, actÚa como antagonista competitivo del receptor activado de la glicoproteÍna plaquetaria IIb/IIIa, con actividad antiplaquetaria. Eptifibatide Chemical Structure
  38. GC33760 ETC-1002 (ESP-55016)

    Bempedoic Acid, ESP-55016

     ETC-1002 (ESP-55016) (ETC-1002) es un inhibidor de ATP-citrato liasa (ACL). ETC-1002 (ESP-55016) Chemical Structure
  39. GC47397 Gemfibrozil-d6

    CI-719-d6

     An internal standard for the quantification of gemfibrozil Gemfibrozil-d6 Chemical Structure
  40. GC48744 Gliclazide-d4 An internal standard for the quantification of gliclazide Gliclazide-d4 Chemical Structure
  41. GC18788 Graphislactone A Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. Graphislactone A Chemical Structure
  42. GC43803 HA-1077 (hydrochloride)

    Fasudil

     Fasudil (HA-1077; AT877) dihidrocloruro es un inhibidor rhoa/roca inespecÍfico y también tiene un efecto inhibitorio en las proteÍnas quinasas, con un KI de 0.33 ⋼ m para el rock111&&&&&&77TRESTO. offlineefficient_models_2022q2.md;M, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively.en_es_2021q4.mdHA-1077 (hydrochloride) is also a potent Ca2+ channel antagonist and vasodilator.en_es_2021q4.md HA-1077 (hydrochloride) Chemical Structure
  43. GC45469 Hexacosanoic Acid-d4   Hexacosanoic Acid-d4 Chemical Structure
  44. GC49496 Homocitrulline-d3

    ε-Carbamyllysine-d3, L-ε-Amino-Carbamoyl-Lysine-d3

     An internal standard for the quantification of homocitrulline Homocitrulline-d3 Chemical Structure
  45. GC43997 KDdiA-PC KDdiA-PC es un tipo de LDL oxidada (oxLDL) y es un ligando para el receptor eliminador de macrÓfagos CD36. KDdiA-PC Chemical Structure
  46. GC44011 KOdiA-PC Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. KOdiA-PC Chemical Structure
  47. GC52497 Lactosylceramide (porcine RBC)

    LacCer

     A sphingolipid Lactosylceramide (porcine RBC) Chemical Structure
  48. GC40142 Lactosylceramides (bovine buttermilk)

    LacCer

     Lactosylceramide (LacCer) is an endogenous bioactive sphingolipid. Lactosylceramides (bovine buttermilk) Chemical Structure
  49. GC52281 Losartan Azide A potential impurity in commercial preparations of losartan Losartan Azide Chemical Structure
  50. GC44093 Lutein

    E 161b, Xanthophyll

     Lutein is a natural yellow carotenoid, which can be found in plants, egg yolks, and in the human retina. Lutein Chemical Structure
  51. GC18241 Lysophosphatidylcholines

    ​Lyso-Lecithins (egg)

    Lysophosphatidylcholines are produced by hydrolysis of the fatty acid of phosphatidylcholine at either the sn-1 or sn-2 position by phospholipase A2 (PLA2) or by lecithin-cholesterol acyltranferase (LCAT), which transfers the fatty acid to cholesterol.

     Lysophosphatidylcholines Chemical Structure
  52. GC49486 Meglutol-d3

    Dicrotalic Acid-d3, 3-hydroxy 3-methyl Glutaric Acid-d3, HMG-d3, 3-methyl-3-Hydroxyglutaric Acid-d3, Medroglutaric Acid-d3, 3-hydroxy-3-Methylglutaric Acid-d3

     An internal standard for the quantification of meglutol Meglutol-d3 Chemical Structure
  53. GC44180 Methylcarbamyl PAF C-16 Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. Methylcarbamyl PAF C-16 Chemical Structure
  54. GC40624 MMP-3 Inhibitor VIII

    Matrix Metalloproteinase-3 Inhibitor VIII, Stromelysin-1 Inhibitor VIII

     Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 Inhibitor VIII Chemical Structure
  55. GC18616 MMP-8 Inhibitor I

    Matrix Metalloproteinase-8 Inhibitor I

     MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. MMP-8 Inhibitor I Chemical Structure
  56. GC20172 N-Isopropylphthalimide N-Isopropylphthalimide Chemical Structure
  57. GC44518 Osteocalcin (1-49) (human) (trifluoroacetate salt) Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Osteocalcin (1-49) (human) (trifluoroacetate salt) Chemical Structure
  58. GC44573 PAz-PC

    Azelaoyl PC, 1Palmitoyl2Azelaoyl PC

     Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. PAz-PC Chemical Structure
  59. GC44616 PGPC

    1-Palmitoyl-2-glutaryl phosphatidylcholine

    PGPC is an oxidized phospholipid that can be formed under conditions of oxidative stress.

     PGPC Chemical Structure
  60. GC44633 Phosphatidylserines (bovine)

    PtdSers (bovine)

     Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (bovine) Chemical Structure
  61. GC18522 Phosphatidylserines (sodium salt)

    L-α-Phosphatidylserine, PtdSer (Soy), Soy PS

     Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (sodium salt) Chemical Structure
  62. GC49340 Pitavastatin lactone-d4 An internal standard for the quantification of pitavastatin lactone Pitavastatin lactone-d4 Chemical Structure
  63. GC44669 POV-PC

    2(5oxovaleryl) Phosphatidylcholine

     Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. POV-PC Chemical Structure
  64. GC49107 Rosuvastatin lactone

    (+)-Rosuvastatin lactone, Rosuvastatin-5S-lactone, RSTL

     The lactone form of rosuvastatin Rosuvastatin lactone Chemical Structure
  65. GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin Rosuvastatin-d6 (sodium salt) Chemical Structure
  66. GC44910 Sodium Hydrogen Sulfide (hydrate)

    NaHS, NSC 158264, Sodium Hydrosulfide

     Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sulfide (hydrate) Chemical Structure
  67. GC45057 TIQ-A TIQ-A es un potente inhibidor de TNKS (poli-ART, PARP), con una IC50 de 24 nM para TNKS2. TIQ-A Chemical Structure
  68. GC48206 Trimethylamine-d9 N-oxide

    TMAO-d9

     An internal standard for the quantification of trimethylamine N-oxide Trimethylamine-d9 N-oxide Chemical Structure

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