Cilofexor (Synonyms: GS-9674) |
| Catalog No.GC18212 |
Cilofexor (GS-9674) es un agonista de FXR no esteroideo potente, selectivo y oralmente activo con un EC50 de 43 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1418274-28-8
Sample solution is provided at 25 µL, 10mM.
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Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC50 = <25 nM in a FRET activity assay). It has FXR agonist activity in a mammalian one hybrid (M1H) assay (EC50 = >100 nM).
Review for Cilofexor
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
Review for Cilofexor
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