Demecarium Bromide (BC-48) |
| Catalog No.GC31190 |
El bromuro de demecarium (BC-48) (BC-48) es un potente inhibidor de la colinesterasa, con una afinidad aparente (Kiapp) de 0,15 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 56-94-0
Sample solution is provided at 25 µL, 10mM.
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Demecarium Bromide (BC-48) is a potent cholinesterase antagonist, with an apparent affinity (Kiapp) of 0.15 μM[1]. Demecarium Bromide (BC-48) is used as a glaucoma agent[2].
Demecarium Bromide (0.125 and 0.5%) causes long-term miosis and decreases intraocular pressure (IOP) in beagles with both normotensive eyes and inherited glaucoma[1].
[1]. Brown JH, et al. Activation and blockade of cardiac muscarinic receptors by endogenous acetylcholine and cholinesterase inhibitors. J Pharmacol Exp Ther. 1982 Oct;223(1):20-4. [2]. Gum GG, et al. Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma. Am J Vet Res. 1993 Feb;54(2):287-93.
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