EX-527 S-enantiomer |
Catalog No.GC13417 |
El enantiÓmero EX-527 S ((S)-EX-527) es un inhibidor potente y selectivo de SIRT1, con una IC50 de 98 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 848193-68-0
Sample solution is provided at 25 µL, 10mM.
Selisistat S-enantiomer (EX-527 S-enantiomer) is the S-enantiomer of Selisistat, with an IC50 of 123 nM for SIRT1. Selisistat S-enantiomer is much more potent than Selisistat R-enantiomer.
References:
[1]. Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.
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