CDK2-IN-4 |
| Catalog No.GC35632 |
CDK2-IN-4 es un inhibidor potente y selectivo de CDK2 con una IC50 de 44 nM para CDK2/ciclina A, muestra una selectividad de 2000 veces sobre CDK1/ciclina B (IC50=86 uM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2079895-42-2
Sample solution is provided at 25 µL, 10mM.
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CDK2-IN-4 is a potent and selective CDK2 inhibitor with an IC50 of 44 nM for CDK2/cyclin A, shows 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM)[1]. cdk2/cyclin A|44 nM (IC50)|Cdk1/cyclin B|86 μM (IC50)
[1]. Coxon CR, et al. Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J Med Chem. 2017 Mar 9;60(5):1746-1767.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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