HIV-1 integrase inhibitor 4 |
Catalog No.GC36235 |
El inhibidor 4 de la integrasa del VIH-1 es un inhibidor de la transferencia de cadena de la integrasa (INST) del VIH-1 con una IC50 de 3,7 nM.
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Cas No.: 1638504-66-1
Sample solution is provided at 25 µL, 10mM.
HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. IC50: 3.7 nM (INST)[1]
HIV-1 integrase inhibitor 4 (compound 4f) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. HIV-1 integrase inhibitor 4 shows potent activity against recombinant HIV IN in biochemical assays and good efficacy in assays done in cell culture against a broad panel of viral mutants carrying the major RAL and DTG IN resistance mutations[1].
[1]. Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11(4):1074-81.
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(Based on Reviews and 37 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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