Imiquimod maleate |
| Catalog No.GC12645 |
El maleato de imiquimod (maleato R 837), un modificador de la respuesta inmunitaria, es un agonista selectivo del receptor tipo toll 7 (TLR7).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 896106-16-4
Sample solution is provided at 25 µL, 10mM.
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Imiquimod maleate is an immune response modifier that acts as a toll-like receptor 7agonist.
In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1].
References:
[1]. Bilu D, et al. Imiquimod: modes of action. Br J Dermatol. 2003 Nov;149 Suppl 66:5-8.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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