Inicio>>Signaling Pathways>> Others>>LP 922056

LP 922056

Catalog No.GC50548

LP 922056 es un inhibidor de pectinacetilesterasa de Notum altamente potente y activo por vía oral con CE50 de 21 nM, 55 nM en ensayos celulares humanos y de ratón, respectivamente.

Products are for research use only. Not for human use. We do not sell to patients.

LP 922056 Chemical Structure

Cas No.: 1365060-22-5

Tamaño Precio Disponibilidad Cantidad
10 mg
132,00 $
Disponible
50 mg
404,00 $
Disponible

Tel:(909) 407-4943 Email: sales@glpbio.com


Reseñas de cliente

Based on customer reviews.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

Notum pectinacetylesterase inhibitor. Activates wnt signalling in vitro (EC50 values are 21 nM in human and 55 nM in mouse cell-based assay). Increases cortical bone thickness in mouse model of bone growth.

Tarver et al (2016) Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase. Bioorg.Med.Chem.Lett 26 1525 PMID:26897593 |Brommage et al (2019) NOTUM inhibition increases endocortical bone formation and bone strength. Bone Res. 7 PMID:30622831

Reseñas

Review for LP 922056

Average Rating: 5 ★★★★★ (Based on Reviews and 21 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for LP 922056

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.