S961 acetate |
| Catalog No.GC61550 |
El acetato S961 es un antagonista del receptor de insulina (IR) selectivo y de alta afinidad con IC50 de 0,048, 0,027 y 630 nM para HIR-A, HIR-B y el receptor del factor I de crecimiento similar a la insulina humana (HIGF-IR) en SPA -ensayo, respectivamente.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1].
S961 also shows high-affinity to Rat IR and Pig IR with IC50s of 0.056 nM and 0.084 nM in PEG-assay, respectively[1].
[1]. SchÄffer L, et al. A novel high-affinity peptide antagonist to the insulin receptor. Biochem Biophys Res Commun. 2008 Nov 14;376(2):380-3.
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