Thalidomide 4'-oxyacetamide-alkylC4-amine |
| Catalog No.GC50464 |
La talidomida 4'-oxiacetamida-alquilC4-amina, un conjugado de enlazador-ligando de ligasa E3 sintetizado que incorpora el ligando de cereblon basado en talidomida y un enlazador, puede usarse en la sÍntesis de PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2245697-86-1
Sample solution is provided at 25 µL, 10mM.
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Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 3 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Winter et al (2015) Drug development. Phthalimide conjugation as a strategy for in vivo target protein degradation. Science 348 1376 PMID:25999370 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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