S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate |
| Catalog No.GC61257 |
El metanosulfonotioato de S-(1-hidroxi-2-metilpropan-2-il) es un enlazador de ADC escindible con glutatiÓn que se utiliza para los conjugados de anticuerpo-fÁrmaco (ADC) y se refiere a la composiciÓn de la cadena de alquilo. El metanosulfonotioato de S-(1-hidroxi-2-metilpropan-2-il) es la porciÓn conectora de las moléculas empleadas para fines de uniÓn de mAb.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2127875-65-2
Sample solution is provided at 25 µL, 10mM.
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S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].
[1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.
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