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Salbutamol

Catalog No.GC71682

Salbutamol (Albuterol) es un agonista de acción corta del receptor beta 2 adrenérgico con actividad oral.

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Salbutamol Chemical Structure

Cas No.: 18559-94-9

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL DMSO)
50,00 $
Disponible
100 mg
45,00 $
Disponible
500 mg
108,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD).

Salbutamol (16 μM, 24 h) significantly induces EMT, migration and invasion by ERK (extracellular signal-regulated kinase) phosphorylation in gastric cancer cells[1].

Salbutamol (5 mg/kg/day, orally, for 2 consecutive weeks) can increase tumor growth in nude mice with gastric cance[1].
Salbutamol (6 mg/kg orally for 4 weeks) has a significant protective effect against STZ -induced skeletal muscle atrophy in diabetic rats[2].

References:
[1]. Lu Y, et al. Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. J Cancer. 2022 Jan 1;13(2):401-412.
[2]. Hong YP, et al. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47(6):436-445.

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