SB-429201 |
| Catalog No.GC64684 |
SB-429201 es un HDAC1 potente y selectivo (IC50~1,5 μM). SB-429201 muestra una preferencia de al menos 20 veces por la inhibiciÓn de HDAC1 sobre HDAC3 y HDAC8.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1027971-34-1
Sample solution is provided at 25 µL, 10mM.
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SB-429201 is a potent and selective HDAC1 (IC50~1.5 μM). SB-429201 displays at least a 20-fold preference for HDAC1 inhibition over HDAC3 and HDAC8[1][2].
[1]. Hu E, et al. Identification of novel isoform-selective inhibitors within class I histone deacetylases. J Pharmacol Exp Ther. 2003;307(2):720-728. [2]. Bieliauskas AV, Pflum MK. Isoform-selective histone deacetylase inhibitors. Chem Soc Rev. 2008;37(7):1402-1413.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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