Stafia-1 |
| Catalog No.GC62559 |
Stafia-1 es un potente inhibidor de STAT5a (K i = 10,9 μM, IC50 = 22,2 μM). Stafia-1 muestra una alta selectividad sobre STAT5b y otros miembros de la familia STAT.
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Cas No.: 2582757-90-0
Sample solution is provided at 25 µL, 10mM.
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Stafia-1 is a potent STAT5a inhibitor (K i=10.9 μM, IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members[1].
Stafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other STAT family members[1].
[1]. Natarajan K, et al. Stafia-1: a STAT5a-Selective Inhibitor Developed via Docking-Based Screening of in Silico O-Phosphorylated Fragments. Chemistry. 2020;26(1):148-154.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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