Terpendole C |
Catalog No.GC45017 |
El terpendol C, producido por Albophoma yamanashiensis, muestra una potente actividad inhibitoria contra la acil-CoA: colesterol aciltransferasa (ACAT).
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Cas No.: 156967-65-6
Sample solution is provided at 25 µL, 10mM.
Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. yamanashiensis and an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 2.1 μM in rat liver microsomes). It also inhibits ACAT in J774 macrophages (IC50 = 0.46 μM) without affecting cell growth.
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